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王勇军

发布者:神经再生重点实验室 发布时间:2016-05-04 游览次数:



王勇军,理学博士,教授。江苏省神经科学学会副理事长兼秘书长。中国解剖学会再生医学专业委员会委员;中国生理学会转化神经专业委员会委员;江苏省“333”工程培养对象,江苏省“六大人才高峰”资助对象。主要研究方向为组织与器官再生的分子调控及系统演变。

国家重点基础研究发展计划骨干(973计划),主持完成国家自然科学基金4项、江苏省自然科学基金1项和江苏省高校基础研究重大项目1项等。获教育部自然科学二等奖1项(排名5)。在Nature Communications, J Biol Chem, Nucleic Acids Res等期刊发表SCI50余篇。E-mail:wyjbs@ntu.edu.cn

研究方向:

以大鼠中枢和周围神经损伤为实验模型,研究炎症因子对损伤神经中胶质细胞的影响及其分子机制;以低等脊椎动物为动物模型,研究自发性脊髓再生过程中炎症因子的功能转换及其对中枢神经再生的影响,从免疫学角度阐述免疫相关因子和中枢神经再生之间的关系。

5年代表性论文:

1. Shen T, Wang Y, Zhang Q, Bai X, Wei S, Zhang X, Wang W, Yuan Y, Liu Y,Liu M, Gu X, Wang Y*. Potentialinvolvement of Snail members in neuronal survival and astrocytic migrationduring the gecko spinal cord regeneration. Front Cell Neurosci. 2017, 11:113.

2.Zhao Y§, Wang Y§ (Co-first), GongJ, Yang L, Niu C, Ni X, Wang Y, Peng S, Gu X, Sun C, Yang Y. Chitosandegradation products facilitates peripheral nerve regeneration by improvingmacrophage-constructed microenvironments. Biomaterials, 2017, 134:64-77.

3. Wang Y§, Zhao Y§,Sun C, Hu W, Zhao J, Li G, Zhang L, Liu M, Liu Y, Ding F, Yang Y, Gu X. Chitosan Degradation Products Promote Nerve Regeneration by Stimulating SchwannCell Proliferation via miR-27a/FOXO1 Axis. Mol Neurobiol. 2016, 53: 28-39.

4. Zhang Q, Wang Y, Man L, Zhu Z, Bai X, Wei S, Liu Y, Liu M, Wang X, GuX, Wang Y*. Reactive oxygen speciesgenerated from skeletal muscles are required for gecko tail regeneration. Sci Rep. 2016, 6:20752.

5.Liu Y*, Zhou Q*, Wang Y*(Co-first), Luo L*, Yang J*, Yang L*, Liu M, Li Y, Qian T, Zheng Y, Li M,Li J, Gu Y, Han Z, Xu M, Wang Y, Zhu C, Yu B, Yang Y, Ding F, Jiang J, Yang H,Gu X. Gekko japonicus genome revealsevolution of adhesive toe pads and tail regeneration. Nature Communications. 2015,6:10033.

6. Bai X, Wang Y, Man L, Zhang Q, Sun C, Hu W, Liu Y, Liu M, Gu X, Wang Y*. CD59 mediatescartilage patterning during spontaneous tail regeneration.Sci Rep. 2015, 5:12798.

7. Dong Y, Gu Y, Huan Y, Wang Y, Liu Y, Liu M, Ding F, Gu X, Wang Y*. HMGB1 does notmediate the inflammatory response in spontaneous spinal cord regeneration: Ahint for CNS regeneration. J Biol Chem, 2013, 288: 18204–18218.

8.Yu B, Qian T, Wang Y, Zhou S, Ding G, Ding F, Gu X. miR-182 inhibits Schwann cell proliferation and migration by targeting FGF9 andNTM, respectively at an early stage following sciatic nerve injury. Nucleic Acids Res. 2012, 40: 10356-10365.

9. Wang Y, Dong Y, Song H, Liu Y, Liu M, Yuan Y, Ding F, Gu X, Wang Y*. Involvement of geckoSNAP25b in spinal cord regeneration by promoting outgrowth and elongation ofneurites. Int J Biochem Cell B. 2012, 44:2288-2298.

10. Wang Y, Gu Q, Dong Y, Zhou W, Song H, Liu Y, Liu M, Yuan Y, Ding F,Gu X, Wang Y*. Inhibition of geckoGSK-3β promotes elongation of neurites and oligodendrocyte processes butdecreases the proliferation of blastemal cells. J cell biochem, 2012, 113:1842-1851.