当前位置: 首页 > 学术队伍

陈 罡

发布者:神经再生重点实验室 发布时间:2015-11-17 游览次数:


陈罡,江苏省特聘教授,教育部新世纪优秀人才。于2008年在中国科学院神经科学研究所获得理学博士(神经生物学)学位,曾任美国哈佛大学、杜克大学博士后、美国杜克大学助理教授,入选江苏省“333”人才工程,江苏省“青蓝工程”,江苏省高校优秀共产党员,南通市青年岗位能手,南通大学“我最喜爱的老师”等。现任江苏省神经科学学会理事,江苏省神经科学学会青年工作委员会副主任委员。曾获江苏省科技进步二等奖。主要研究方向是神经损伤与功能恢复。已发表SCI 收录论文27篇,其中第一作者或通讯联系人12篇,影响因子大于10的有5篇。

代表性论文:

1. GangChen*, Yong Ho Kim*, Hui Li, Hao Luo, Da-Lu Liu, Zhi-Jun Zhang,Mark Lay, Wonseok Chang, Yu-Qiu Zhang and Ru-Rong Ji. PD-L1 inhibits acute andchronic pain by suppressing nociceptive neuron activity via PD-1.Nature Neuroscience. 2017,May 22. doi: 10.1038/nn.4571. (*共同第一作者).This article was highlighted by Nature.

2. Gang Chen, Xin Luo, M Yawar Qadri, Temugin Berta, andRu-Rong Ji.Sex-dependentglial signaling in pathological pain: Distinct role of spinal microglia andastrocytes. Neuroscience Bulletin.2017. June 5. Doi:10.1007/s12264-017-0145-y (通讯作者).

3.Chen G*, XieRG*,Gao YJ*, Xu ZZ*, Zhao LX, Bang SB, Berta T,Park CK, Lay M, Chen W, Ji RR.β-arrestin-2regulates NMDA receptor function inspinal lamina II neurons and duration of persistent pain. Nature Communications 7, Articlenumber: 12531 (2016) doi:10.1038/ncomms12531 (*共同第一作者).

4.BertaT*, Qadri Y.J.* , Chen G* , Ji RR.MicroglialSignaling in Chronic Pain with a Special Focus on Caspase 6, p38 MAPKinase, andSex Dependence. J Dent Res. 2016Jun 15. pii: 0022034516653604. (*共同第一作者).

5.ShenYT,Gu Y, Su WF, Zhong JF, Jin ZH, Gu XS, ChenG. Rab27b is involved in lysosomal exocytosis and proteolipid proteintrafficking in oligodendrocytes. NeuroscienceBulletin.2016. August; 32 (4):331-340. (通讯作者). 封面文章。

6. Su WF, Gu Y, Wei ZY, Shen YT,Jin ZH, Yuan Y, Gu XS, Chen G.Rab27a/Slp2-a complex is involved in Schwann cell myelination. Neural Regeneration Research. 2016, 11(11):1830-1838.(通讯作者).

7.ShenYT, Yuan Y, SuWF, Gu Y, Chen G. Theroles of lysosomal exocytosis in regulated myelination.J NeurolNeuromed.2016, 1(5):4-8. (通讯作者).

8. ChenG*,ParkCK, Xie RG,Ji RR*. Intrathecal bone marrow stromal cells inhibitneuropathicpain via TGF-b secretion. The Journal of Clinical Investigation. 2015;125(8):3226-3240 (*共同通讯作者). Thiswork was introduced by many news sites, includingScienceNews, Neuroscience News, Medical Daily, Daily Mail, Duke Today, PainResearch Forum, etc.

9. ChenG, Park CK, Xie RG, BertaT, Nedergaard M, Ji RR. Connexin-43 induceschemokine release from spinal cord astrocytes to maintain late-phaseneuropathic pain in mice.Brain. 2014 Aug;137(Pt 8):2193-2209. (单独第一作者).

10. ChenG*,Zhang Z J, Wei Z Y, Cheng Q, Li X, Li W, Duan S M, Gu X S*. Lysosomalexocytosis in Schwann cells contributes to axon remyelination. Glia.2012, 60(2): 295-305. (*共同通讯作者)

11.Zhang Z*, Chen G*, Zhou W*,Song A, Xu T, Luo Q, Wang W, Gu XS, Duan S. Regulated ATPrelease from astrocytes through lysosome exocytosis. Nat Cell Biol. 2007,9:945-953. (*共同第一作者) Thisarticle has been cited by web of science more than 220 times.

12.Chen G, Li HM, Chen YR, Gu XS, Duan S.Decreased estradiol release from astrocytes contributes to theneurodegeneration in a mouse model of Niemann-Pick disease type C. Glia.2007, 55:1509-1518.(单独第一作者).